The folks at X-Setup are shutting down and releasing their shareware for free -
http://www.x-setup.net/

"X-Setup Pro is a so-called "hacker" or "tweaker" program. It allows you to change 1,900 settings that are normally hidden deeply in some configuration-files like the registry fast and easily. It runs on any Windows version, is clutter-free, easy to use, extensible, powerful, covers any aspect of your computer and has more configuration options than any other tweaker."

Runs on Win 9x to Vista (haven't checked Windows 7). Download at MajorGeeks and BetaNews.
http://www.majorgeeks.com/down.....d4083.html

Portable:
http://majorgeeks.com/X-Setup_Pro_Porta ... d5565.html