In 1993, NASA launched the Space Shuttle Endeavour with an IBM ThinkPad 750 on board.
On a mission to repair the Hubble Space Telescope, the crew used a notebook computer in space for the first time. The IBM ThinkPad 750 was used to observe color schematics and sketches of the telescope.
Learn more at http://www-03.ibm.com/ibm/history/exhibits/space/space_thinkpad.html.